Slow and progressive damage of the liver by Chronic liver diseases leads to liver cirrhosis with problems in liver function and problems related to structural changes in the liver tissue.
Functional Problems are directly related to poor function of liver cells such as: 1. Poor pigment (bilirubin) clearance causing jaundice, 2. Reduced production of protein albumin results in fluid collection in the belly and swelling of feet, 3. Low production of prothombin and other blood clotting proteins results in bleeding tendency, 4. Low elimination of toxins such as ammonia from the blood results in mental confusion and coma, 5. Absorption of vitamins and nutrients is affected
Structural Changes caused by repeated scarring of the liver results in raised pressure in the portal vein (supplying blood and oxygen to the liver). This creates alternate channels for blood flow which are under high pressure and can give rise to severe bleeding.
This is the most common cause of liver cirrhosis in most parts of the world.Liver cancer can develop in 20% of these cirrhotics.
One of the most common inherited disorders among caucasians. Incidence is 1 per 2-7000 population.
Most commonly seen in young women with prominent hyperglobulinemia. In type I IACAH elevated titers of non organ specific antinuclear antibodies.
Biliary Atresia is a defect in the development of the bile ducts that drain from the liver into the intestines that is characterized by obliteration of the biliary system, resulting in obstruction to bile flow.
BCS is a rare disorder wherein there is wide spread clotting of the veins draining the liver.
Cancer of the gallbladder is a malignant tumor arising from the gallbladder.
Chronic viral hepatitis is the principal cause of chronic liver disease, cirrhosis and hepatocellular carcinoma in the world.
Choledochal cysts are cystic dilatation of the bile duct, outside the liver or within which are congenital anomalies of the bile duct.
When the liver gets damaged uniformly by toxins, bile, drugs, alcohol, hepatitis infections or by certain genetic conditions, the normal tissue gets replaced with scars.
Drug-induced hepatitis is rare and is caused by toxic exposure to certain medications, vitamins, herbal remedies, or food supplements.
Haemochromatosis (HC) also called the 'bronze diabetes' is a disorder in iron metabolism.
Hepatitis A is an acute infectious disease of the liver caused by the hepatitis A virus
Hepatitis B is caused by the infectious Hepatitis B virus (HBV)
Hepatitis C virus seeks the liver as the primary target for its multiplication and growth. Nearly 3% of the world population (170 million people) is affected by this virus. It is primarily transmitted from one person to another through blood to blood contact. With various break through in medical science, treatment for Hepatitis C has never been simpler and effective.
Dr.Rajasekar provides Oral treatment for Hepatitis C
Hepatitis D, a disease caused by a small circular enveloped RNA virus
Hepatitis E is a viral hepatitis (liver inflammation) caused by infection with a virus called hepatitis E virus (HEV)
When the liver shrinks from disease, the resistance to blood flow increases several fold causing Portal Hypertension.
Auto immune disease of Liver
PSC mainly affects males and is characterized by chronic inflammation of the bile ducts resulting in stricture formation and obliteration of the duct lumen. In 70% of the patients it is associated with inflammatory bowel disease (IBD).
During pregnancy, there are significant normal physiologic changes in liver function. Complications include Hepatitis, Cholestatis of Pregnancy, Acute Fatty Liver of Pregnancy etc.
Bacterial abscess of the liver is relatively rare.
Liver cell adenoma is common in young women and may be related to the use of oral contraceptive medications.
When liver cell failure occurs the waste products accumulate in the blood, slowing down the brain function. The coma can progress through four stages, the earliest being slowness of speech or altered sleep wake cycle and the last stage being deep state of coma. In most occasions coma is reversible completely unless the liver failure is very advanced.
Liver cancer rarely occurs in a normal liver. Non cancerous tumours are rare. It is common in livers infected with hepatitis B or C viruses and in cirrhotic livers.
An autosomal recessive disease.
An autosomal recessive disease of copper metabolism.